Εργασίες Ελλήνων ιατρών
2/4/2021

NASH limits anti-tumour surveillance in immunotherapy-treated HCC

Hepatocellular carcinoma (HCC) can have viral or non-viral causes1–5. Non-alcoholic steatohepatitis (NASH) is an important driver of HCC. Immunotherapy has been approved for treating HCC, but biomarker-based stratification of patients for optimal response to therapy is an unmet need6,7. Here we report the progressive accumulation of exhausted, unconventionally activated CD8+PD1+ T cells in NASH-affected livers.

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2/4/2021

From the origin of NASH to the future of metabolic fatty liver disease

From the origin of NASH to the future of metabolic fatty liver disease Andreas Geier, Dina Tiniakos, Helmut Denk, Michael Trauner

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18/2/2021

Alcoholic liver disease and autoimmune hepatitis: Sometimes a closer look under the surface is needed

Alcoholic liver disease and autoimmune hepatitis: Sometimes a closer look under the surface is needed

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3/11/2020

Reconsidering the management of patients with cancer with viral hepatitis in the era of immunotherapy

Reconsidering the management of patients with cancer with viral hepatitis in the era of immunotherapy Dimitrios C Ziogas,1 Frosso Kostantinou,1 Evangelos Cholongitas,1 Amalia Anastasopoulou,1 Panagiotis Diamantopoulos,1 John Haanen,2 Helen Gogas1

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30/4/2020

Wilson disease: 30-year data on epidemiology, clinical presentation, treatment modalities and disease outcomes from two tertiary Greek centers

Maria Tampaki, Nikolaos K. Gatselis, Spyridon Savvanis, Emmanouil Koullias, Asterios Saitis, Stella Gabeta, Melanie Deutsch, Emmanouil Manesis, Georgios N. Dalekos and John Koskinas

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27/4/2020

Association of TIM-3 with BCLC Stage, Serum PD-L1 Detection, and Response to Transarterial Chemoembolization in Patients with Hepatocellular Carcinoma

Maria Tampaki, Evangelos Ionas, Emilia Hadziyannis , Melanie Deutsch , Katerina Malagari and John Koskinas

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22/4/2020

Current practice and contrasting views on discontinuation of nucleos(t)ide analog therapy in chronic hepatitis B

Emilia Hadziyannis and Stephanos Hadziyannis

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22/4/2020

NAFLD and autoimmune hepatitis: Do not judge a book by its cover

George N. Dalekos, Nikolaos K. Gatselis, Kalliopi Zachou, George K. Koukoulis

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10/4/2020

Validating and expanding the Baveno VI criteria for esophageal varices in patients with advanced liver disease: a multicenter study

Adonis A. Protopapas, Theodora Mylopoulou, Vasileios P. Papadopoulos, Kiriaki Vogiatzi, Ioannis Goulis, Konstantinos Mimidis

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3/3/2020

Immunological biomarkers as indicators for outcome after discontinuation of nucleos(t)ide analogue therapy in patients with HBeAg-negative chronic hepatitis B

Hariklia Kranidioti | Spilios Manolakopoulos | George Kontos| Michael S. Breen | Anastasia Kourikou | Melanie Deutsch| Maria Ester Quesada-Del-Bosque | Rocio T. Martinez-Nunez | Mohammed M. Naiyer | Christopher H. Woelk | Tilman Sanchez-Elsner| Emilia Hadziyannis | George Papatheodoridis | Salim I. Khakoo

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26/2/2020

NAFLD and autoimmune hepatitis: Do not judge a book by its cover

George N. Dalekos, Nikolaos K. Gatselis,Kalliopi Zachou, George K. Koukoulis

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26/2/2020

Factors Associated With Progression and Outcomes of Early Stage Primary Biliary Cholangitis

Patients usually receive a diagnosis of primary biliary cholangitis (PBC) at an early stage, based on biochemical analyses. We investigated the proportion of patients who progress to moderate or advanced PBC and factors associated with progression and patient survival.

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14/1/2019

Hellenic Association for the Study of the Liver Clinical Practice Guidelines: Autoimmune hepatitis

George N. Dalekos, John Koskinas, George V. Papatheodoridis Institute of Internal Medicine and Hepatology, Larissa; University Hospital of Larissa; National and Kapodistrian University of Athens, “Hippokratio” General Hospital of Athens, Athens; Medical School of National and Kapodistrian University of Athens, “Laiko” General Hospital of Athens, Athens, Greece

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17/4/2018

The British Society of Gastroenterology/UKPBC primary biliary cholangitis treatment and management guidelines

Gideon M Hirschfield,Jessica K Dyson, Graeme J M Alexander, Michael H Chapman, Jane Collier, Stefan Hübscher, Imran Patanwala, Stephen P Pereira, Collette Thain, Douglas Thorburn, Dina Tiniakos, Martine Walmsley, George Webster, David E J Jones

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3/10/2017

Increased cholestatic enzymes in two patients with long-term history of ulcerative colitis: consider primary biliary cholangitis not always primary sclerosing cholangitis

Increased cholestatic enzymes in two patients with long-term history of ulcerative colitis: consider primary biliary cholangitis not always primary sclerosing cholangitis Erietta Polychronopoulou, Vasiliki Lygoura, Nikolaos K Gatselis, George N Dalekos

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7/7/2017

Geoepidemiology, clinical manifestations and outcome of primary biliary cholangitis in Greece

Nikolaos K. Gatselis, Kalliopi Zachou, Vasiliki Lygoura, Kalliopi Azariadis, Pinelopi Arvaniti, Elias Spyrou, Georgia Papadamou, George K. Koukoulis, George N. Dalekos, Eirini I. Rigopoulou

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16/12/2016

Efficacy of prophylactic antiviral therapy and outcomes in HBsAg-negative, anti-HBc-positive patients receiving chemotherapy: a real-life experience

Nikolaos Papadopoulosa, Melanie Deutschc, Spilios Manolakopoulosc, Chrysoula Bitsia, Helias Michalakeasb,Helias Poulakidasb, Eftychia Tsironie, Stavroula Giannoulic, George V. Papatheodoridisd, John Koskinasc and Dimitrios Pectasides

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17/10/2016

Severe liver involvement in two patients with long-term history of fever : remember familial Mediterranean fever

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30/9/2016

Molecular diagnostic testing for primary biliary cholangitis.

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30/9/2016

von Willebrand factor and procoagulant imbalance independently predict outcome in patients with cirrhosis and thrombocytopenia.

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30/9/2016

Reliability and applicability of two-dimensional shear-wave elastography for the evaluation of liver stiffness.

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30/9/2016

Is elimination of HCV possible in a country with low diagnostic rate and moderate HCV prevalence? The case of Greece

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30/9/2016

Evaluation of neutrophil/leukocyte ratio and organ failure score as predictors of reversibility and survival following an acute-on-chronic liver failure event

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30/9/2016

Discontinuation of oral antivirals in chronic hepatitis B: A systematic review

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30/9/2016

Extensively drug-resistant bacteria are an independent predictive factor of mortality in 130 patients with spontaneous bacterial peritonitis or spontaneous bacteremia

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30/9/2016

TGF-β signaling is activated in patients with chronic HBV infection and repressed by SMAD7 overexpression after successful antiviral treatment

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30/9/2016

Alterations in the iron homeostasis network: A driving force for macrophage-mediated hepatitis C virus persistency

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30/9/2016

Circulating adiponectin levels in type 2 diabetes mellitus patients with or without non-alcoholic fatty liver disease: Results of a small, open-label, randomized controlled intervention trial in a subgroup receiving short-term exenatide

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28/3/2016

PAGE-B predicts the risk of developing hepatocellular carcinoma in Caucasians with chronic hepatitis B on 5-year antiviral therapy

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28/3/2016

A real-world study focused on the long-term efficacy of mycophenolate mofetil as first-line treatment of autoimmune hepatitis

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3/2/2014

Autoimmune hepatitis – current management and challenges

Autoimmune hepatitis remains a major diagnostic and therapeutic challenge. The clinician, the hepato-pathologist and the laboratory personnel need to become more familiar with different expressions of the disease, interpretation of liver histology and autoimmune serology.

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